Tastes great, less filling! Randomized trial comparing perceived palatability of dexamethasone preparations in children

Abstract

Dexamethasone has been shown to be effective for croup and acute asthma exacerbations in children. Current guidelines do not recommend 1 systemic corticosteroid over another, but there is some evidence to suggest dexamethasone may result in fewer gastrointestinal adverse effects. A meta-analysis aimed at determining the equivalence or superiority of dexamethasone to prednisone or prednisolone for pediatric acute asthma exacerbations found no difference in the relative risk of relapse between the 2 groups, and patients receiving dexamethasone were less likely to experience vomiting.