Abstract

Modern Research in Dentistry Targeting the Tumor Stroma for Oral Cancer Therapy Takehito Ouchi1*, Satoru Morikawa1 and Seiji Asoda1 1Department of Dentistry and Oral Surgery, Japan *Corresponding author: Takehito Ouchi, Department of Dentistry and Oral Surgery, Shinjuku-ku, Tokyo, 160-8582, Japan Submission: July 18, 2019;Published: July 30, 2019 DOI: 10.31031/MRD.2019.04.000586 ISSN:2637-7764Volume 4 Issue 3

Highlights

  • Histopathological diagnosis is commonly used to identify oral cancer

  • Spindle cell carcinoma (SpCC) is a subtype of poorly differentiated oral squamous cell carcinoma (OSCC) diagnosed by immunostaining of pathological specimens [5]

  • Our group demonstrated that a cetuximab-resistant recurrent SpCC sample expressed the mesenchymal stem cells (MSCs) markers platelet-derived growth factor receptor α (PDGFRα) and Nestin

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Summary

Introduction

Histopathological diagnosis is commonly used to identify oral cancer. morphological diagnosis alone cannot clarify the biological malignancy and prognosis of this disease. Targeting the Tumor Stroma for Oral Cancer Therapy Histopathological diagnosis is commonly used to identify oral cancer. Findings from cancer stem cell research and cancer genetic analysis help guide the design of cancer studies.

Results
Conclusion

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