Abstract

Cancer is still the second most common cause of death because of genetic mutations in DNA (deoxyribonucleic acid) sequences. The standard target-directed strategy, which is one of the biggest hurdles in anti-cancer research is dealing with the significance of target function in healthy cells. Cancer cells also suffer from a variety of mutations, alterations in gene duplication, and chromosomal abnormalities, all of which have an immediate impact on the effectiveness of anticancer medications at various developmental stages. Cancer medicine development is challenging due to a combination of these characteristics, which also contribute to lower clinical licensure success rates than in other therapeutic categories. The pathophysiology and molecular characteristics of prevalent cancer types are the main topics of the current review. The search for herbal-based alternatives that lessen resistance brought on by cancer therapy and exert chemo-protective properties is motivated by the fact that the currently available chemotherapeutic medications, also known as combination chemotherapy, are linked to a number of negative effects. This review revised the list of important substances that may improve the effectiveness of cancer treatment in order to offer fresh perspectives

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