Abstract

Purpose: Ischaemia/reperfusion (I/R) is a primary cause of myocardial injury during cardiac surgery resulting in the release of damage-associated molecular patterns (DAMPs), which can induce a sterile inflammatory response in the myocardial penumbra. Targeted temperature management (TTM) is established for neuroprotection but the cardioprotective effect remains to be elucidated. Therefore, we investigated the effect of TTM on cell viability, oxidative stress and DAMPs release during oxygen-glucose deprivation (OGD) in cardiomyocytes.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.