Targeted Temperature Management in Postcardiac Arrest Syndrome: A Single-Center Experience with 47 Patients

Abstract

Our aim in this study is to retrospectively analyze the results of Targeted Temperature Management (TTM) treatment in our intensive care unit. Following the ethics committee's approval, the demographic data, cardiac arrest history, the follow-up process, and the final status of patients who were applied TTM in Sakarya University Training and Research Hospital Anesthesia Intensive Care Unit between January 2017 and December 2019 were recorded. Then, the effect of these parameters on mortality was evaluated using regression analysis. Data of 47 patients who met the study criteria were analyzed. The mean age of the patients was 50 ± 16 and 14 (29.8%) patients were female. The duration of cardiopulmonary resuscitation (CPR) was 22.35 ± 16.08 minutes, 35 (74.5%) patients had a witness to arrest, 25 (53.2%) patients were arrested in the hospital, and 13 (27.7%) patients had shockable rhythm. It was determined that 60% of the patients died, 20% of them were care patients with poor neurological outcomes and 20% of them were discharged outpatient with good neurological outcomes. Age, development of acute renal failure, requiring vasopressor, high APACHE scores, and length of hospital stay were found to be independent risk factors for mortality.