Targeted identification of adverse events in coronary artery disease patients based on patient-reported outcomes.

Abstract

Can focusing the adverse events search to patients with poor patient-reported outcome help in targeting adverse event detection? Coronary artery revascularization patients of the Kuopio University Hospital from June 2012 to August 2014 categorized into those with clinically significant improvement (15D score change ≥0.015, n=81) or deterioration (change ≥-0.015, n=64) in post-intervention health-related quality of life. Major complications (27 vs 9%, p=0.004) or post-intervention infections (16 vs 5%, p=0.031) were more common among those with deteriorated score. They also tended to have more cardiovascular (19 vs 9%, p=0.071) and minor complications (16 vs 7%, p=0.118). Patient-reported outcomes may potentially help in targeting the adverse events search so that a larger number of adverse events can be identified for efficient learning from them.