Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster.

Abstract

genesisVolume 34, Issue 1-2 p. 80-82 UAS LinesFree Access Targeted expression of dominant negative proteasome mutants in drosophila melanogaster John M. Belote, Corresponding Author John M. Belote [email protected] Department of Biology, Syracuse University, Syracuse, New YorkDepartment of Biology, Syracuse University, 130 College Place, Syracuse, NY 13244Search for more papers by this authorEric Fortier, Eric Fortier Department of Biology, Syracuse University, Syracuse, New YorkSearch for more papers by this author John M. Belote, Corresponding Author John M. Belote [email protected] Department of Biology, Syracuse University, Syracuse, New YorkDepartment of Biology, Syracuse University, 130 College Place, Syracuse, NY 13244Search for more papers by this authorEric Fortier, Eric Fortier Department of Biology, Syracuse University, Syracuse, New YorkSearch for more papers by this author First published: 12 September 2002 https://doi.org/10.1002/gene.10131Citations: 40AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. LITERATURE CITED Baumeister W, Walz J, Zühl F, Seemüller E. 1998. The proteasome: paradigm of a self-compartmentalizing protease. Cell 92: 367– 380. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401– 415. Chain DG, Schwartz JH, Hedge AN. 1999. Ubiquitin-mediated proteolysis in learning and memory. Mol Neurobiol 20: 125– 142. Covi JA, Belote JM, Mykles DL. 1999. Subunit compositions and catalytic properties of proteasomes from developmental temperature-sensitive mutants of Drosophila melanogaster. Arch Biochem Biophys 368: 85– 97. Freeman M. 1997. Personal communication to FlyBase available from http://flybase.bio.indiana.edu:82/.bin/fbidq.html?FBrf0091569. Hampton RY, Bhakta H. 1997. Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase. Proc Natl Acad Sci USA 94: 12944– 12948 Hershko A, Ciechanover A. 1998. The ubiquitin system. Annu Rev Biochem 67: 425– 479. Holden JJ, Suzuki DT. 1973. Temperature-sensitive mutations in Drosophila melanogaster XII. The genetic and developmental effects of dominant lethals on chromosome 3. Genetics 73: 445– 458. Hoyt MA. 1997. Eliminating all obstacles: regulated proteolysis in the eukaryotic cell cycle. Cell 91: 149– 151. Huang Y, Baker RT, Fischer-Vize JA. 1995. Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene. Science 270: 1828– 1831. Jesenberger V, Jentsch S. 2002. Deadly encounter: ubiquitin meets apoptosis. Nat Rev Mol Cell Biol 3: 112– 121. Myung J, Kim KB, Crews CM. 2001. The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev 21: 245– 273. Naidoo N, Song W, Hunter-Ensor M, Sehgal A. 1999. A role for the proteasome in the light response of the timeless clock protein. Science 285: 1737– 1741. Saville KJ, Belote JM. 1993. Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit. Proc Natl Acad Sci USA 90: 8842– 8846. Schweisguth F. 1999. Dominant-negative mutations in the β2 and β6 proteasome subunit genes affect alternative cell fate decisions in the Drosophila sense organ lineage. Proc Natl Acad Sci USA 96: 11382– 11386. Smyth KA, Belote JM. 1999. The dominant temperature-sensitive lethal DTS7 of Drosophila melanogaster encodes an altered 20S proteasome beta-type subunit. Genetics 151: 211– 220. Tsang, T, Copeland V, Bowden GT. 1991. A set of cloning vectors for rapid and versatile adaptation of restriction fragments. BioTechniques 10: 330. Zhou MY, Clark SE, Gomez-Sanchez CE. 1995. Universal cloning method by TA strategy. BioTechniques 19: 34– 35. Citing Literature Volume34, Issue1-2Special Issue: GAL4/UAS in Drosophila September ‐ October 2002Pages 80-82 ReferencesRelatedInformation