Targeted Chemical Processing Initiating Biosome Action-Potential-Matched Artificial Synapses for the Brain-Machine Interface.

Abstract

A great gap still exists between artificial synapses and their biological counterparts in operation voltage or stimulation duration. Here, an artificial synaptic device based on a thin-film transistor with an operating voltage (-50-50 mV) analogous to biological action potential is developed by targeted chemical processing with the help of supercritical fluids. Chemical molecules [hexamethyldisilazane (HMDS)] are elaborately chosen and brought into the target interface to form charge receptors through supercritical processing. These charge receptors with the ability of capturing electrons mimic neurotransmitter receptors in terms of mechanism and constitute key players accounting for the synaptic behaviors. The relatively lower electrical barrier height contributes to an action-potential-matched operating voltage and considerably low power consumption (∼1 pJ/synaptic event), minimizing the divide with biological synapse for a seamless linkage to the biosystem or brain-machine interface. The stable synaptic behaviors also lead to near-ideal accuracy in pattern recognition. Moreover, this methodology that introduces chemical groups into a target interface can be viewed as a platform technology that could be adapted to other conventional devices with suitable chemical molecules to reach designed synaptic behaviors. This environmentally friendly and low-temperature processing method, which can be performed even after device fabrication, has the potential to play an important role in the future development of bionic devices.