Abstract
Target Organ Damage in Hypertension
Highlights
Cardiovascular disease has been associated to a low level of chronic inflammatory state which may be an important mechanism leading to organ damage in hypertensive patients
Erectile dysfunction may be the first manifestation of endothelial dysfunction in hypertensive men, and for this reason it can be indicated as a risk marker of cardiovascular events [5, 6]
Trindade et al were able to identify pulse pressure, HDLcholesterol, and C-reactive protein as variables associated to increased carotid intima-media thickness (IMT) in treated hypertensive women with no history of diabetes or cardiovascular events
Summary
Cardiovascular disease has been associated to a low level of chronic inflammatory state which may be an important mechanism leading to organ damage in hypertensive patients. The same authors published original papers reporting that T-regulatory lymphocytes were able to prevent vascular injury mediated by angiotensin II and aldosterone by suppressing inflammation and oxidative stress and improving endothelial function in experimental models of hypertension [1, 2]. Vascular disease is the main topic in three review papers of this collection.
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