Abstract
Positively charged gold nanoparticles ((+)AuNPs) are electrostatically adsorbed on the negatively charged aptamers and the solution displays a blue color due to the aggregation of the (+)AuNPs, while the binding of the target lysozyme with the aptamers reduces the charge of the aptamers, which stabilizes the (+)AuNPs and the (+)AuNPs solution remains red in color.
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