Abstract

-Dear Editor, Paliperidone is an atypical antipsychotic drug formed by one of the active metabolites of risperidone, 9-hydroxirisperione.1 The drug demonstrates its effects by antagonizing central dopamine type-2 (D2) and serotonin type-2 (5HT2A) receptors. It could be used in acute stage and maintenance treatment of schizophrenia, and schizoaffective and bipolar disorders. In this letter, a case of male patient, who developed tardive dyskinesia due to paliperidone palmitate, is scrutinized. The objective of this letter is to call attention to the extrapyramidal side effects of stock paliperidone such as tardive dyskinesia, albeit rare.

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