Abstract
BackgroundStudies of disinfection by-products in drinking water and measures of adverse fetal growth have often been limited by exposure assessment lacking data on individual water use, and therefore failing to reflect individual variation in DBP exposure.MethodsPregnant women recruited to the Born in Bradford cohort study completed a questionnaire which covers water exposure. Information was collected on water consumption, showering, bathing and swimming. Water exposure data from a subset of 39 women of the cohort are described here.ResultsMean total tap water intake was 1.8 l/day, and women on average spent 146 minutes per week showering and bathing. Most tap water intake occurred at home (100% for unemployed, 71.8% for employed). Differences between age groups were observed for total tap water intake overall (p = 0.02) and at home (p = 0.01), and for bottled water intake (p = 0.05). There were differences between ethnic groups for tap water intake at home (p = 0.02) and total tap water intake at work (p = 0.02). Total tap water intake at work differed by income category (p = 0.001). Duration per shower was inversely correlated with age (Spearman's correlation -0.39, p = 0.02), and differed according to employment status (p = 0.04), ethnicity (p = 0.02) and income (p = 0.02).ConclusionThis study provides estimates of water exposure in pregnant women in a multi-ethnic population in the north of England and suggests differences related to age, employment, income and ethnicity. The findings are valuable to inform exposure assessment in studies assessing the relationship between DBPs and adverse birth outcomes.
Highlights
Studies of disinfection by-products in drinking water and measures of adverse fetal growth have often been limited by exposure assessment lacking data on individual water use, and failing to reflect individual variation in Disinfection by-products (DBPs) exposure
A sizeable proportion of the women were educated to degree level (35.9%). 48.7% were of White British origin and 38.5% were of Pakistani origin
For employed women some tap water ingestion occurs at work and this should be considered in DBP exposure assessment
Summary
Studies of disinfection by-products in drinking water and measures of adverse fetal growth have often been limited by exposure assessment lacking data on individual water use, and failing to reflect individual variation in DBP exposure. There is some evidence to suggest that exposure to DBPs during pregnancy may be related to measures of compromised fetal growth, e.g. term low birth weight, or intrauterine growth retardation [3,4], findings are inconsistent and the evidence remains inconclusive. A major limitation in previous studies has been crude or incomplete exposure assessment; in particular, studies have often ignored individual variation in water use, ignoring a potential source of variation in DBP exposure. We are investigating the relationship between DBPs and measures of fetal growth in the Born in Bradford birth cohort [5]. In this paper we describe patterns of water exposure within a subset of the cohort
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