Abstract
As a phenolic acid, tannic acid can be classified into a polyphenolic group. It has been widely studied in the biomedical field of science because it presents unique antiviral as well as antibacterial properties. Tannic acid has been reported to present the activity against Influeneza A virus, Papilloma viruses, noroviruses, Herpes simplex virus type 1 and 2, and human immunodeficiency virus (HIV) as well as activity against both Gram-positive and Gram-negative bacteria as Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes, Enterococcus faecalis, Pseudomonas aeruginosa, Yersinia enterocolitica, Listeria innocua. Nowadays, compounds of natural origin constitute fundaments of material science, and the trend is called “from nature to nature”. Although biopolymers have found a broad range of applications in biomedical sciences, they do not present anti-microbial activity, and their physicochemical properties are rather poor. Biopolymers, however, may be modified with organic and inorganic additives which enhance their properties. Tannic acid, like phenolic acid, is classified into a polyphenolic group and can be isolated from natural sources, e.g., a pure compound or a component of a plant extract. Numerous studies have been carried out over the application of tannic acid as an additive to biopolymer materials due to its unique properties. On the one hand, it shows antimicrobial and antiviral activity, while on the other hand, it reveals promising biological properties, i.e., enhances the cell proliferation, tissue regeneration and wound healing processes. Tannic acid is added to different biopolymers, collagen and polysaccharides as chitosan, agarose and starch. Its activity has been proven by the determination of physicochemical properties, as well as the performance of in vitro and in vivo studies. This systematics review is a summary of current studies on tannic acid properties. It presents tannic acid as an excellent natural compound which can be used to eliminate pathogenic factors as well as a revision of current studies on tannic acid composed with biopolymers and active properties of the resulting complexes.
Highlights
Human organisms are exposed to different external factors which may cause diseases and which pose a threat to people’s lives
The results confirmed the ability of hydrogels with silver nanoparticles modified by Tannic acid (TA) to affect viral attachment, impede penetration and cell-to-cell transmission, profound differences in the activity displayed by the tested preparations toward Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) were noted
Anti-infectious properties have been demonstrated for tannins isolated from green tea extract. They are active against Streptococcus pyogenes, which was discussed in the paper by Hull Vance et al The results obtained during studies indicated that the extract addition inhibited the attachment of the bacteria to the kidney epithelial cells in a dose dependent manner [48]
Summary
Human organisms are exposed to different external factors which may cause diseases and which pose a threat to people’s lives. There is a growing interest in compounds which may be extracted from natural sources and which have unique antimicrobial properties. Their application has been considered in the form of diet supplements with or as raw materials, i.e., for medical or packaging purposes. There is a growing interest in naturally derived compounds which may be isolated from natural sources and used as raw compounds for biomaterials preparation Materials based on both types of natural polymers, proteins, and polysaccharides have been found as biocompatible and non-toxic for the human body [11,12,13]. It suggests that each extraction method should be followed by the final product characterization [20,21]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
