Tandem technologies in chromatographic analysis

Abstract

The acquisition of chemical compounds information from samples depends on the separation as well as detection techniques. Usually, it is difficult to achieve the separation and identification of all components in complex samples by a simple one-dimensional chromatographic method. Thus, tandem technologies, which mainly include column tandem connection techniques, detector tandem connection techniques, and multidimensional chromatography, have aroused widespread interest. In this paper, advances in the three aforementioned tandem techniques (not including chromatography tandem mass spectrometry) since 2010 are discussed. Typical applications for obtaining more comprehensive and accurate information from samples are also reviewed. Finally, the development of chromatographic tandem technologies is summarized and future prospects are examined.