Abstract
A report on the first EMBO conference entitled “Next Gen Immunology—From Host Genome to the Microbiome: Immunity in the Genomic Era”, held at the Weizmann Institute of Science, Israel, 14–16 February, 2016.
Highlights
A report on the first EMBO conference entitled “ Gen Immunology—From Host Genome to the Microbiome: Immunity in the Genomic Era”, held at the Weizmann Institute of Science, Israel, 14–16 February, 2016
He further described a difference in bacteria metabolizing human milk oligosaccharide (HMO) in different countries, with a possible contribution to host immunity
The effect of the maternal microbiome on offspring health was underlined by Dan Littman (Skirball Institute of Biomolecular Medicine, New York University, USA) who showed that simulating a viral infection with poly I:C at gestational day 12.5 leads to autism spectrum disorder (ASD)-like symptoms in mice offspring
Summary
Julie Segre (National Institutes of Health, USA) presented a computational pipeline for the examination of the skin microbiome, allowing the exploration of different strains and of the pangenome versus the core genome of different species. Ramnik Xavier (Broad Institute, USA) examined infants genetically predisposed to type I diabetes and showed that the disease is anticipated by a reduction of diversity in gut microbial species.
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