Takayasu's arteritis manifesting as scoliosis and hypertention: a case report and review of literatures

Abstract

Objective To investigate the clinical characteristics, diagnosis, and treatment of Takayasu's arteritis (TA) for further understanding of this disease. Methods We reported a case of TA manifesting as scoliosis and hypertention and reviewed the related literatures. Results TA, commonly seen in young females and children, is a chronic agranulomatous arteritis of unknown cause, manifesting mainly as systemic inflammatory responses and ischemic signs of the involved organs. The diagnosis of TA is often delayed because of lack of specific clinical features at the acute inflammatory period and the efficacy is usually unsatisfactory due to the occurrence of organic ischaemia. Conclusions In order to rule out TA, patients with multi-systemic and multi-viscera lesions should have comprehensive examination,especially for those with hypertension, pulseless, and vascular bruits. Early ultrasonography and computed tomography can enhance the early diagnostic rate. Imaging studies, as well as angiography are needed to look into the conditions of involved arteries. Proper treatment should be administered according to the location,degree, and size of the involved arteries. Key words: Takayasu's arteritis; Scoliosis; Hypertension