Abstract
<strong>Background:</strong> Takayasu’s arteritis (TA) has been associated with many conditions. Herein described is a case of TA in a patient with rheumatic fever complicated with Sydenham’s chorea. <strong>Case Report:</strong> A 17-year-old female presented at age 6 with rheumatic fever followed by chorea a month later. At the age of 16, she developed a blood pressure discrepancy between the arms and faint pulses. Computed tomography angiography revealed diffuse aortic involvement and narrowing of the arteries. <strong>Discussion:</strong> The presence of rheumatic fever and Sydenham’s chorea in TA raises the possibility of an immunological basis for the pathogenesis of the disease.
Highlights
Takayasu’s arteritis (TA) is a rare chronic large-vessel vasculitis of unknown etiology
First reported by the Japanese ophthalmologist Takayasu in 1908, TA has an age of onset between the second and fifth decades of life, and females are more commonly affected than males, in an estimated ratio of 6.6:1.1–3 Since the original description, the disease has been associated with various conditions, including rheumatoid arthritis and other collagen vascular diseases, syphilis, tuberculosis, rheumatic fever and other streptococcal infections, mitral stenosis, and rheumatic heart disease.[3,4,5]
Its association with rheumatoid arthritis and lupus erythematosus disease raises the possibility of a shared primary or secondary autoimmune mechanism contributing to the pathogenesis of the disease.[5]
Summary
Takayasu’s Arteritis in a Patient with Sydenham’s Chorea: is There an Association?. Thiago Cardoso Vale[1], Ricardo Oliveira Horta Maciel[1], Debora Maia[1], Rogerio Beato1 & Francisco Cardoso1* 1 Movement Disorders Clinic, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
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