Abstract

BackgroundTakayasu arteritis is a rare, chronic, granulomatous systemic vasculitis of unknown etiology and a few cases have been reported in pregnancy. In pregnancies concomitant with Takayasu arteritis or after diagnosis, Takayasu arteritis negatively affects pregnancy by increasing 13-fold the odds of complications such as hypertensive disorders. The best recommendations in this scenario are still to be made.Case presentationWe present a case of 21-year-old, gravid 1, Mexican woman of Mestizo descent with chronic hypertension diagnosed since she was 15-years old who presented severe hypertension during pregnancy (early second trimester); the diagnosis of hypertensive disorder of pregnancy was ruled out requiring first-line and second-line antihypertensive therapy without serious associated maternal or fetal morbidity.ConclusionsTakayasu arteritis and pregnancy play an important role in maternal and fetal outcomes. Efforts should be made to further investigate the Takayasu arteritis diagnosis in pregnant women with refractory hypertension.

Highlights

  • Takayasu arteritis is a rare, chronic, granulomatous systemic vasculitis of unknown etiology and a few cases have been reported in pregnancy

  • Takayasu arteritis (TA) is a primary systemic vasculitis of unknown etiology that leads to stenotic and occlusion changes [1]. It was first described in a Japanese woman in 1908 by the ophthalmologist Mikito Takayasu who reported a case of a 21-year-old woman with the association of retinal arteriovenous anastomosis, syncope, and pulseless superior extremities [2]

  • The pathophysiology of TA has been described as a chronic inflammatory disease affecting the aorta and its branches in a progressive pattern, which can lead to secondary hypertension, retinopathy, cardiac pathology, stroke, and death at an early age [4]

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Summary

Conclusions

Our acquired experience indicates that BP levels in TA and pregnancy play an important role in maternal and fetal outcomes.

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