Abstract
Here, we describe the adaptation to the field of autism of an original procedure denominated the "Ruggiero-Klinghardt Protocol" (RK Protocol), a procedure that represents a paradigm change with significant implications for chronic conditions where immunotherapy may prove effective; that is from silent infections to neurodegenerative diseases, autism and cancer. In the context of autism, the modified RK Protocol that we propose here serves the purpose of discovering hidden infections that may be associated with autism and contribute to its symptoms. This notion is consistent with the observation that immune modulating molecules are effective in autism treatment. In the RK Protocol modified for autism, we introduce the Autism Treatment Evaluation Checklist (ATEC), a more objective and sophisticated method of evaluation compared with the Clinical Global Impression of Improvement scale that was previously used, independently of the RK Protocol, to evaluate the effectiveness of immunotherapy of autism. The modifications that we present in this study take advantage of the experience that has accumulated in the two years after the publication of the original RK Protocol. Similarly to the original RK Protocol, this new version offers the advantage of being safe and relatively inexpensive since it does not require sophisticated instruments; because of this, it can be implemented in different parts of the world. We envisage that implementation of the RK Protocol modified for autism may contribute to decrease the burden of the disease as it enables prevention, early diagnosis and treatment on a large scale.
Highlights
The Ruggiero-Klinghardt Protocol (RK Protocol) described in 2017 in the American Journal of Immunology (Ruggiero and Klinghard 2017), was developed with the goal of improving the sensitivity of diagnosis and efficacy of therapy in chronic conditions. This protocol was originally developed for persistent Lyme disease, we realized that the full protocol, or parts of it, may be useful in other chronic conditions, including autism, with particular reference to optimization of immunotherapeutic approaches
Autonomic Response Testing (ART) is a manual biofeedback technique developed by Dr Klinghardt that has the objective of evaluating the presence and/or persistence of spirochete and other infectious and noninfectious noxae that may be found in conjunction with and possibly responsible for, persistent Lyme disease
ART was repeated; this second ART had the scope of evaluating whether therapeutic ultrasound had been successful in mobilizing pathogenic noxae from sanctuaries or reservoirs making them "visible" to the Therapist performing ART
Summary
The Ruggiero-Klinghardt Protocol (RK Protocol) described in 2017 in the American Journal of Immunology (Ruggiero and Klinghard 2017), was developed with the goal of improving the sensitivity of diagnosis and efficacy of therapy in chronic conditions This protocol was originally developed for persistent Lyme disease, we realized that the full protocol, or parts of it, may be useful in other chronic conditions, including autism, with particular reference to optimization of immunotherapeutic approaches. As far as the use of ultrasonography in the present protocol is concerned, this technique can be utilized to refine the diagnostic hypotheses suggested by ART or it can be performed independently of ART In the latter case, here we describe the areas of the body that we recommend to study because of their potential involvement in the pathogenesis of autism. To study all the organs and the regions of the body listed in the step
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