Abstract
Different ratios of a resorbable phosphate glass (ICEL) and a bioactive silicate glass (CEL2) were co-sintered to obtain 3D porous scaffolds by gel-cast foaming method. The scaffold morphology, crystalline phases and compressive strength were studied. All the scaffolds showed a 3D structure with highly interconnected pores. The ICEL/CEL2 co-sintering resulted in a lower shrinkage leading to higher scaffold porosity (more than 70 vol%) compared to pure ICEL and CEL2 (about 65 vol%). Tuning ICEL/CEL2 ratio allowed the modulation of the scaffold resorption rate, with weight loss ranging from 20% to 75% after soaking for 3 months in simulated body fluid. Scaffolds containing higher amount of CEL2 silicate glass, resulted in a very high bioactivity.In vitrobiological test showed no toxic effect of the scaffolds on human osteoblast-like cells.
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