Abstract

Cancer Drug Resistance is an open access journal, focusing on pharmacological aspects of drug resistance and its reversal, molecular mechanisms of drug resistance and drug classes, etc. Both clinical and experimental aspects of drug resistance in cancer are included.

Highlights

  • Paola Perego Molecular Pharmacology Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy

  • Novel therapeutic strategies to improve the efficacy of ovarian carcinoma treatment are emerging from both basic and translational research efforts

  • As a large family of enzymes with more than 600 members, several E3 ubiquitin ligases participate in key cellular processes for survival of cancer cells, thereby contributing to chemoresistance

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Summary

Introduction

Tackling cisplatin resistance in ovarian cancer: what can we do? Novel therapeutic strategies to improve the efficacy of ovarian carcinoma treatment are emerging from both basic and translational research efforts. In this Special Issue, approaches to improve the armamentarium to fight ovarian carcinoma are presented, thereby providing an overview of selected aspects of ovarian cancer biology that can be exploited to improve treatment.

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