Abstract
The actions of mammalian tachykinins on neurons of rat coeliac-superior mesenteric ganglia (C-SMG) were examined using intracellular recording in isolated preparations. Application of substance P, neurokinin A and neurokinin B produced fast and slow depolarizations in the ganglion cells. The two responses were clearly distinguishable in their electrophysiological characteristics. The results suggest that different receptor mechanisms are involved in fast and slow depolarizing actions of tachykinins in rat C-SMG cells.
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