T26. Mental Context Reinstatement Balances Retrieval of Fear Versus Safety Memories in the Human Brain

Abstract

As Pavlovian extinction serves as a model for anxiety treatment, there is motivation to better understand how extinction memories are encoded, stored, and expressed so as to bolster the strength of clinical treatment. Here, we used multivariate pattern classification (MVPA) of functional MRI in humans to decode a multivariate signature selective to encoding and 24-hour retrieval of extinction memories.