T2 mapping vs T2 weighted imaging in the detection of myocardial oedema

Elisa Mcalindon,Tom Johnson,Jessica Harris,Chiara Bucciarelli-Ducci,Peter Weale,Andreas Baumbach,David Smith

doi:10.1186/1532-429x-14-s1-p266

Abstract

Background The “gold standard” CMR sequence for assessing the myocardial oedema or area at risk following an acute coronary syndrome is controversial. T2 Short Tau Inversion Recovery (T2-STIR) is in widespread clinical use but can lack robustness. Steady state free precession oedema imaging (SSFP/ ACUT2E) has emerging data to support it as a more reproducible method for area at risk (AAR) assessment. We tested a novel T2 mapping method to AAR. The potential benefit of this method is that the numerical output of the method is largely independent of myocardial motion, instrumental errors (eg surface coil normalisation methods). The aim of this study was to compare the novel T2 mapping method with the two existing methods of assessing AAR (T2STIR and SSFP/ACUT2E).

Highlights

The “gold standard” CMR sequence for assessing the myocardial oedema or area at risk following an acute coronary syndrome is controversial
30 slices in 10 patients day 2-4 following acute myocardial infarction were analysed by 3 sequences (T2-STIR, ACUT2E, and T2 mapping)
We found a good agreement between T2 Short Tau Inversion Recovery (T2-STIR) and ACUT2E

Summary

Introduction

The “gold standard” CMR sequence for assessing the myocardial oedema or area at risk following an acute coronary syndrome is controversial. T2 Short Tau Inversion Recovery (T2-STIR) is in widespread clinical use but can lack robustness. Steady state free precession oedema imaging (SSFP/ ACUT2E) has emerging data to support it as a more reproducible method for area at risk (AAR) assessment. We tested a novel T2 mapping method to AAR. The potential benefit of this method is that the numerical output of the method is largely independent of myocardial motion, instrumental errors (eg surface coil normalisation methods). The aim of this study was to compare the novel T2 mapping method with the two existing methods of assessing AAR (T2STIR and SSFP/ACUT2E)

Objectives

Methods

Results