Abstract
Objective: Non-invasive methods have been investigated as an alternative to biopsy in assessing liver fibrosis. This study aimed to
 evaluate the relationship between liver T1 relaxation time and liver fibrosis as a non-invasive alternative method.
 Patients and Methods: This study analyzed 1.5T magnetic resonance (MR) images of 86 patients retrospectively. The participants were
 divided into two groups: patients with chronic hepatitis and the control group. Native variable flip angle (VFA) T1 mapping technique
 was used to estimate liver T1 relaxation time. T1 mapping sequence, T2* mapping sequence, and image analysis were performed. The
 liver size, the spleen size, the liver T1 relaxation time, and the liver T2* relaxation time were recorded.
 Results: The T1 relaxation time was 758.4 ± 121.1 ms in the chronic hepatitis group and 600.2 ± 67 ms in the control group. The T1
 relaxation time of the patient group was significantly higher than that of the control group (p
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