Abstract
T/NK-cell lymphoma of nasal-type was described in 1933 as a malignant medio-facial granuloma. The diagnosis of this rare condition is clinical and immunohistopathological. We report an original case of cutaneous T/NK lymphoma of the nasal type revealed by cutaneous ulcerations.
Highlights
The cutaneous lymphoma T/NK nasal type is malignant proliferation of cytotoxic T lymphocytes (CTL)
Cutaneous histology was leaning towards cutaneous lymphoma T/NK nasal type of high grade objectifying an atypical lymphocytic infiltrate with angiocentric disposition (Figure 2)
We report an original case of a cutaneous T/NK Lymphoma Nasal type revealed by skin ulcerations stressing how important to refer to this diagnosis in presence of chronic cutaneous ulcerations resistant to usual treatments
Summary
The cutaneous lymphoma T/NK nasal type is malignant proliferation of cytotoxic T lymphocytes (CTL). This is a particular entity associated with Epstein-Barr virus (EBV) infection, which explains, by its high prevalence in Asia, South and Central America. The mucocutaneous review showed ulcerated skin lesions of the anterior aspect of the right forearm, thighs and legs without mucosal involvement (Figure 1). Cutaneous histology was leaning towards cutaneous lymphoma T/NK nasal type of high grade objectifying an atypical lymphocytic infiltrate with angiocentric disposition (Figure 2). A CT scan of facial bones showed thickening of the right nostril. The disease evolved rapidly; the patient died after his first chemotherapy session (CHOP Protocols)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
