T-Cell Receptor Excision Circles in Newborns With Congenital Heart Disease

Abstract

BT Davey, RW Elder, MM Cloutier. J Pediatr. 2019;213:96–102.e2 The authors of this study sought to inform their hypothesis that patients with congenital heart disease (CHD) had lower T-cell receptor excision circles (TRECs) than the general population, and low TREC levels in CHD patients are associated with infections leading to hospitalization. Five hundred and seventy-five patients with a diagnosis of structural CHD born between October 2011 and April 2016 were enrolled in this study. They were recruited from the two major Connecticut children’s hospitals, Connecticut Children’s Medical Center and Yale-New Haven Children’s Hospital, which …