Abstract
A 16-year-old girl presented to the out patient department in Grande International Hospital with complaints of fever since 3 weeks, tonsillitis and multiple lymphadenopathy. Fine needle aspiration cytology from one of the cervical lymph nodes showed atypical lymphoid cells with prominent nucleoli in some cells; hence, a diagnosis of Non Hodgkin lymphoma was made. Bone marrow aspiration and biopsy also showed presence of similar atypical lymphoid cells. One of the lymph nodes was also excised for purpose of immunohistochemistry, and the biopsy showed effacement of lymph node architecture with diffuse proliferation of intermediate sized atypical lymphoid cells. These tumor cells showed positivity for CD3, TdT, and Ki-67. A diagnosis of T-cell lymphoblastic lymphoma was made.Lymphoblastic lymphomas are rare, accounting for 2% of all lymphomas, of which majority are of T-cell type. TCLL usually occurs in young males. In addition to lymphadenopathy, other common sites of involvement include mediastinum, CNS and bone marrow. It runs an aggressive course and overall survival of patients is poor.
Highlights
Lymphomas are less common in Asian patients than most Caucasians
Following is a case of a rare type of T-cell lymphoma, which was diagnosed by bone marrow aspiration with biopsy and ine needle aspiration cytology and biopsy with immunohistochemistry of lymph nodes
On the other hand showed scattered atypical lymphoid cells similar to those seen in the lymph node
Summary
Lymphomas are less common in Asian patients than most Caucasians. The incidence in South Asians has been shown to be only about 3/100,000 cases, whereas it has been shown to be up to 16/100,000 cases in some European and American populations. Patients present with multiple and large lymphadenopathy along with indings like mediastinal mass and other B symptoms that help us diagnose these cases. After morphological diagnosis of lymphoma has been made, immunohistochemistry should. Following is a case of a rare type of T-cell lymphoma, which was diagnosed by bone marrow aspiration with biopsy and ine needle aspiration cytology and biopsy with immunohistochemistry of lymph nodes
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