Abstract
Abstract It has been shown that the t-amyloxycarbonyl group (AOC group) can be introduced quite readily into amino acid esters by using t-amyl chloroformate as a reagent, and that the AOC group can be cleaved as smoothly as the t-butoxycarbonyl group (BOC group) under acidic conditions. Since this reagent is much easier to prepare than any other reagents used for the introduction of the BOC group, the new procedure is considered to be of great use in the practical synthesis of complicated peptides. 3-Methyl-3-pentoxycarbonylamino acids were also prepared by following the same procedure as was used in the case of AOC-amino acids.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
