Abstract
Background: Colorectal cancer (CRC) is the second-leading cause of cancer deaths. Morbidity and mortality could be rapidly reduced through higher uptake and adherence to CRC screening. Information on longer-term screening adherence comes from organized programs that lack a comparison group. Systems of Support to Increase Colorectal Cancer Screening and Follow-Up (SOS) is an ongoing trial testing a centralized mailed and phone-based program to increase long-term CRC screening adherence. We hypothesized that, compared to usual care, intervention-arm patients would have more time in compliance with CRC screening guidelines over 5 years.
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