Abstract
Three key features are representative for systemic sclerosis (SSc), including (i) prevalent vascular lesions and endothelial dysfunction, (ii) fibrosis and (iii) immune abnormalities with consequent occlusive vascular complications. Insufficiently data is actually provided about lipid profile and possible implication in vascular disorder in SSc.
Highlights
Three key features are representative for systemic sclerosis (SSc), including (i) prevalent vascular lesions and endothelial dysfunction, (ii) fibrosis and (iii) immune abnormalities with consequent occlusive vascular complications
Adverse lipid pattern, especially low HDL-C, is commonly reported in SSc, anti-SCL70-positive forms; the significance for early accelerated atherosclerosis and the identification of patients predisposed to commonly develop thrombotic complications remain to be validated by future studies
Significantly lower HDL-C and TC (p
Summary
Three key features are representative for systemic sclerosis (SSc), including (i) prevalent vascular lesions and endothelial dysfunction, (ii) fibrosis and (iii) immune abnormalities with consequent occlusive vascular complications. Data is provided about lipid profile and possible implication in vascular disorder in SSc
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