Systemic sclerosis – agonistic auto-antibodies directed against the angiotensin receptor type 1 and the endothelin receptor type A and their effects on immune cells

Abstract

BackgroundSystemic sclerosis (SSc) is characterised by autoimmunity, vasculopathy and fibrosis. The functional link between these three pathophysiological components is still missing. Recent research suggests an involvement of the vasoconstrictive soluble...