Abstract
The review deals with the problem of generalized osteoporosis (OP) in psoriatic arthritis (PsA). Works published in the past 15 years were sought in the Medline using the keywords «psoriatic arthritis», «osteoporosis», and «osteoporosisassociated fractures» (fragility fractures, low-energy fractures, and osteoporotic fractures). The paper includes the data of studies on the frequency of OP and fractures, the risk factors of OP, and the impact of drug therapy on bone status in patients with PsA.
Highlights
Обзор посвящен проблеме генерализованного остеопороза (ОП) при псориатическом артрите (ПсА)
The review deals with the problem of generalized osteoporosis (OP) in psoriatic arthritis (PsA)
Works published in the past 15 years were sought in the Medline using the keywords «psoriatic arthritis», «osteoporosis», and «osteoporosisassociated fractures»
Summary
Обзор посвящен проблеме генерализованного остеопороза (ОП) при псориатическом артрите (ПсА). При сравнении абсолютных значений МПК при ПсА и псориазе без признаков артрита оказалось, что Z-критерий у пациентов с ПсА был достоверно ниже, чем у больных псориазом: в поясничном отделе позвоночника он составлял в среднем -1,16±0,6 и -0,32±1,1 г/см2 (p=0,011) и в проксимальном отделе бедра -0,79±0,63 и -0,25±1,05 г/см2 (р=0,025) соответственно [6].
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