Abstract
Guillermo Ruiz-Irastorza and colleagues (March 31, p 1027)1Ruiz-Irastorza G Khamashta MA Casteltino G Hughes GRV Systemic lupus erythematosus.Lancet. 2001; 357: 1027-1032Summary Full Text Full Text PDF PubMed Scopus (255) Google Scholar review major advances in clinical issues related to systemic lupus erythematosus (SLE). However, new results on central nervous system SLE and the upcoming role of positron emission tomography (PET) have not been included.In central nervous system SLE, functional (metabolic) brain lesions visualised by fluorine-18-labelled fluoro-2-deoxy-D-glucose PET might be a risk factor for subsequent structural brain damage seen on magnetic resonance imaging.2Weiner SM Otte A Schumacher M et al.Alterations of cerebral glucose metabolism indicate progress to severe morphological brain lesions in neuropsychiatric systemic lupus erythematosus.Lupus. 2000; 9: 386-389Crossref PubMed Scopus (32) Google Scholar PET imaging of the brain could be a powerful tool for the diagnosis of manifest or even subclinical central nervous system involvement in SLE and to correlate well with its clinical course.3Weiner SM Otte A Schumacher M et al.Diagnosis and monitoring of central nervous system involvement in systemic lupus erythematosus: value of F18 fluorodeoxyglucose PET.Ann Rheum Dis. 2000; 59: 377-385Crossref PubMed Scopus (107) Google Scholar Guillermo Ruiz-Irastorza and colleagues (March 31, p 1027)1Ruiz-Irastorza G Khamashta MA Casteltino G Hughes GRV Systemic lupus erythematosus.Lancet. 2001; 357: 1027-1032Summary Full Text Full Text PDF PubMed Scopus (255) Google Scholar review major advances in clinical issues related to systemic lupus erythematosus (SLE). However, new results on central nervous system SLE and the upcoming role of positron emission tomography (PET) have not been included. In central nervous system SLE, functional (metabolic) brain lesions visualised by fluorine-18-labelled fluoro-2-deoxy-D-glucose PET might be a risk factor for subsequent structural brain damage seen on magnetic resonance imaging.2Weiner SM Otte A Schumacher M et al.Alterations of cerebral glucose metabolism indicate progress to severe morphological brain lesions in neuropsychiatric systemic lupus erythematosus.Lupus. 2000; 9: 386-389Crossref PubMed Scopus (32) Google Scholar PET imaging of the brain could be a powerful tool for the diagnosis of manifest or even subclinical central nervous system involvement in SLE and to correlate well with its clinical course.3Weiner SM Otte A Schumacher M et al.Diagnosis and monitoring of central nervous system involvement in systemic lupus erythematosus: value of F18 fluorodeoxyglucose PET.Ann Rheum Dis. 2000; 59: 377-385Crossref PubMed Scopus (107) Google Scholar Systemic lupus erythematosusAuthors' reply Full-Text PDF
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
