Abstract
The article described modern literature data on the diagnosis of the nervous system lesions in patients with systemic lupus erythematosus. There described the differential diagnosis of neurolupus and multiple sclerosis. There described common features and differences of manifestations of the nervous system lesions in patients with systemic lupus erythematosus and multiple sclerosis, as well as the treatment strategy of both diseases. Additionally, we described own data from two observable clinical cases. One of which demonstrates the clinical and diagnostic similarity of neurolupus and multiple sclerosis. The second clinical case shows the possibility of combining the two described diseases in one patient.
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