Abstract
R Goswami, AB Blazquez, R Kosoy, A Rahman, A Nowak-Wʁgrzyn, MC Berin. J Allergy Clin Immunol. 2017;139(6):1885–1896.e9 Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E–mediated food allergy in infants, and its pathophysiology is poorly understood. The investigators characterized allergen-responsive cells in the peripheral blood of subjects undergoing supervised food challenge for FPIES. Patients 1 to 21 years of age previously diagnosed with FPIES underwent oral food challenge (OFC) in a clinical research unit to determine resolution. During OFC, the challenge food was administered in 3 equal portions over 30 minutes, and OFC results were deemed positive if emesis and/or diarrhea occurred in concert with an …
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