Abstract
The aim was to evaluate the systemic arterial compliance (SAC) in patients with essential arterial hypertension (AH) and different plasma total renin (PTR) levels. 29 patients with moderate to severe AH according to their plasma total renin level were divided in 2 groups: 1st -11 patients with PTR level > 400 ng/l; 2nd -18 patients with PTR level < 300 ng/l. Plasma renin concentration was measured by immunoradiometric assay with 2 monoclonal antibodies to active renin (plasma treated with trypsin). All patients were done carotid applanation tonometry. Patients of the 1st group characterized higher pulse blood pressure (68±6 vs 44 ±7 mm Hg, p < 0,05) and lower SAC (7,6 ± 0,8 vs 10,2 ± 0,7 ml/mmHg X 10, p < 0,05), but the same mean systolic and diastolic blood pressure (178 ±14,5/100 ± 7 vs 175 ±12,3/105 ± 14 mm Hg, NS) In spite of equal systolic and diastolic blood pressure levels patients with high PTR level had worse large artery mechanical properties, than patients with normal or low PTR level.
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