Abstract

DARE-BV1 is a novel, highly viscous single dose 2% clindamycin phosphate vaginal gel being investigated as a new treatment for bacterial vaginosis. In a recently completed large, randomized multi-center, placebo-controlled study, DARE-BV1 demonstrated a clinical cure of 70.5% vs. 35.6% in the placebo group (p < 0.001) at Days 21-30. The objective of this study was to determine the systemic and vaginal pharmacokinetics (PK) of DARE-BV1.

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