Abstract
IDENTIFICATION of the sentinel lymph node, a marker for metastatic disease, is used increasingly for the surgical management of melanomas and tumors of the head and neck, breast, thyroid, and genitourinary and gastrointestinal tracts. 1 Isosulfan blue (Lymphazurin; Ben Venue Laboratories, Bedford, OH) is the agent most commonly used, occasionally in conjunction with technetium sulfur colloid. Allergic reactions to this dye were reported previously during lymphangiography. 2,3 We report a systemic reaction associated with use of isosulfan blue for detection of the axillary sentinel node in breast cancer.
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