Abstract
Purpose To systematically review randomised and observational evidence of peri-procedural and long-term effects of CEA, CAS and Medical Treatment Alone (MTA) for individuals with substantial carotid stenosis. To discuss the contribution of observational evidence in informing implications of changing disease risks and procedural characteristics on best treatment strategies in categories of patients.
Highlights
The most effective treatment of carotid stenosis in different types of patients is currently uncertain
We reviewed Randomized Control Trials (RCTs) reporting peri-procedural and/or long-term risks of Carotid Endarterectomy (CEA) vs Medical Treatment Alone (MTA) and CEA vs Carotid Artery Stenting (CAS)
A systematic review identified observational studies studying peri-procedural and long-term effects of CEA or CAS that recruited more than 500 participants and followed them for at least 30 days
Summary
The most effective treatment of carotid stenosis in different types of patients is currently uncertain. Systematic review of randomised and observational evidence of effects of treatments of carotid stenosis to prevent stroke Kusal Lokuge1*, Alison Halliday2, Richard Bulbulia3, Alastair Gray1, Borislava Mihaylova1
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