Systematic review of existing literature regarding the prevalence of pediatric atopic dermatitis in Honduras

Abstract

BackgroundAtopic dermatitis (AD) is an inflammatory skin condition, often multifactorial in origin, and most commonly manifests during childhood. Although there remains a deficit in literature, current data suggests Honduras may have the highest prevalence and severity of AD among all Latin American countries. ObjectiveTo assess the current prevalence of pediatric AD in Honduras and evaluate existing gaps in available literature to monitor disease burden. MethodsA comprehensive literature search was performed in March 2023. Articles were removed if they were published before 2007, were of the incorrect study design, or were focused on countries outside of Honduras. The articles were independently reviewed by two authors. ResultsThe initial literature search yielded 174 studies, of which seven met inclusion criteria. AD prevalence rates in children in Honduras ranged from 0.7%-40.0%. LimitationsLimitations include elements of study design, analytic methods, study populations, and limited articles. ConclusionThere appears to be a disproportionately higher prevalence and disease burden of pediatric AD in Honduras. Future research should acquire accurate data to further understand the prevalence, incidence, and severity of AD in Honduras.