Abstract
Background: Breast cancer is the most common malignancy and the second leading cause of cancer-related death in females worldwide. Progesterone receptors (PRs) are expressed in increased quantities in well-differentiated or 'low-grade' cancers and are associated with a good prognosis we demonstrated a relationship between the presence of PRs and the use of adjuvant hormonal therapy with better responses according to all QoL parameters that were evaluated. The use of SERMs/CB of these tumors also seems favorable to all responses to specific QoL questions. Tamoxifen and Allelactone are significant observations, in reduced incidence of symptoms and vasomotor symptoms, respectively. It is interesting to identify the PRs when proposing or not using adjuvant therapy, especially aromatase inhibitors. Our study shows improvement in vasomotor symptoms using a SERM/CB as a useful therapeutic option in hormone-sensitive breast cancer. If these findings are validated in further research, they should be more widely disseminated to professionals involved in patient care. We found that ER-negative/PR-negative tumor patients had better initial subjective QoL regardless of the adjuvant treatment used. Our study can help assess patient responses to treatment with SERMs, AIs, and/or chemotherapy. However, this method of presenting the response of node-negative tumors to adjuvant treatment could be a powerful, artificially validated concept and could more generally summarize the patient's overall subjective satisfaction regarding breast cancer therapy. In contrast, the appearance of the facilitator was a confusing factor in the majority of questionnaires, as this should be a variable that is already influencing the response to the questionnaires used.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
