Abstract
Ca-P coatings on Ti implants have demonstrated good osseointegration capability due to their similarity to bone mineral matter. Three databases (PubMed, Embase, and Web of Science) were searched electronically in February 2021 for preclinical studies in unmodified experimental animals, with at least four weeks of follow-up, measuring bone-to-implant contact (BIC). Although 107 studies were found in the initial search, only eight experimental preclinical studies were included. Adverse events were selected by two independent investigators. The risk of bias assessment of the selected studies was evaluated using the Cochrane Collaboration Tool. Finally, a meta-analysis of the results found no statistical significance between implants coated with Ca-P and implants with etched conventional surfaces (difference of means, random effects: 5.40; 99% CI: −5.85, 16.65). With the limitations of the present review, Ca-P-coated Ti surfaces have similar osseointegration performance to conventional etched surfaces. Future well-designed studies with large samples are required to confirm our findings.
Highlights
Titanium (Ti) is one of the most widely used materials for the manufacture of dental and orthopaedic implants due to its mechanical properties, chemical stability, and excellent biocompatibility [1]
The osseointegration of implants has been defined as a direct and functional connection between the bone and the implant, where the macroscopic and microscopic characteristics of the implant surface are of great importance
Lack of osseointegration is often due to poor bone formation around the implant surface, leading to insufficient fixation of the implant [2]
Summary
Titanium (Ti) is one of the most widely used materials for the manufacture of dental and orthopaedic implants due to its mechanical properties, chemical stability, and excellent biocompatibility [1]. The quality of implants depends on the properties of their surfaces; the modification of these surfaces, with the aim of achieving optimal osseointegration and shortening waiting times for functional loading, has become an area of great interest for researchers and is under constant evolution. The osseointegration of implants has been defined as a direct and functional connection between the bone and the implant, where the macroscopic and microscopic characteristics of the implant surface are of great importance. The deposition of calcium-phosphate (Ca-P) coatings on the implant surface has received significant attention due to the chemical similarity to natural bone mineral. Describe the rationale for the review in the context of what is already known
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
