Abstract
Along with membrane viscosity, interleaflet friction determines the dynamics of membrane deformation. The two leaflets that form a lipid membrane must slide past each other when the membrane bends, as occurs when vesicles are formed, or membrane tethers are pulled. Existing measurements of interleaflet friction are sparse, examining a single type of lipid, dye, and substrate, which does not give any conclusive answers to how changing these factors will affect the measured interleaflet friction. A recently developed method applies high shear stresses to supported lipid bilayers formed in microfluidic channels, resulting in a tank treading motion where the upper leaflet of the bilayer slides overtop of the bottom leaflet.
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