Abstract

A portable wireless brain–machine interface (BMI) system is highly valuable in neuroscience research, especially for experiments in freely behaving animals, which are not feasible using conventional medical instrumentation. A successful BMI system is much more than a simple collection of individual circuit blocks. There are many practical issues and challenges that need to be carefully addressed. This chapter presents the design of a general–purpose wireless sensor-brain–machine interface system: the PennBMBI. In addition to bench testing, two animal experiments using the system are presented in detail. The first experiment studies perception augmentation through modulated electrical stimulation of certain regions in the somatosensory cortex. In this experiment, rats navigate a watermaze using only brain stimulation to inform their location relative to a hidden platform. The second experiment studies hippocampal gamma-slow oscillation coupling in macaques. Bidirectional stimulation and recording were conducted in freely behaving macaques during sedation, awake, and sleep. Implementation and experimental results are presented and discussed in detail.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.