Abstract
A system has been developed to measure the effects of ultrasound on membrane electrical properties and muscle contractile parameters. A specially designed muscle bath was constructed. Measurement instrumentation for glass microelectrodes and an isometric force transducer were interfaced to a Gould transient recorder and a PDP 11/03 computer. Electrical and contractile measurements on electrically stimulated muscle were made simultaneously with resolution sufficient to observe changes in the rate of rise of the action potential. At present the system is used to study the effects of ultrasound on rat left ventricular papillary muscle.
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