Abstract

Background: After years of declining incidence in many countries, syphilis infection has reemerged as a major public health problem in the last decade. Concomitant infection with HIV can cause syphilis to have atypical characteristics.

Highlights

  • After years of declining incidence in many countries, rates of concomitant infection of findings can involve the skin as well as organs that are rarely affected in HIVnegative individuals such as the eyes (Gaudio, 2006; Lynn, 2004; Wöhrl, 2007)

  • Palmoplantar eruption must be searched in any patient with ocular inflammation to suggest the diagnosis of syphilis

  • This rare combination is likely to be associated with patients suffering from human immunodeficiency virus (HIV) infection

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Summary

Introduction

After years of declining incidence in many countries, rates of concomitant infection of findings can involve the skin as well as organs that are rarely affected in HIVnegative individuals such as the eyes (Gaudio, 2006; Lynn, 2004; Wöhrl, 2007). We present three cases of syphilis causing palmoplantar rash and ocular disease. After years of declining incidence in many countries, syphilis infection has reemerged as a major public health problem in the last decade. Concomitant infection with HIV can cause syphilis to have atypical characteristics

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