Abstract
Syphilis is a chronic infectious process caused by the spirochete Treponema pallidum. In the pregnant woman, syphilis is generally quite easily treated. Long term effects for the mother are rare. Infection during pregnancy may result in spontaneous abortion, stillbirth or premature delivery. The most devastating manifestations are seen in infants born with congenital syphilis. In the HIV-infected pregnant woman who also is infected with syphilis, treatment with the standard regimes may be inadequate. The recent increase in syphilis among women in their childbearing years requires physicians to reacquaint themselves with this disease. The risk factors, manifestations of syphilis, interpretation of serological tests, and management guidelines for the exposed mother are presented.
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