Abstract
In the present study we analyzed uptake of radiolabeled dopamine by intact synaptosomes and purified synaptic vesicles isolated from the dorsal striatum of mice with constitutive inactivation of all three synuclein-coding genes and wild type mice. Synuclein deficiency substantially compromised the uptake of this neurotransmitter by synaptic vesicles whereas had no effect on synaptosomal dopamine uptake.
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