Abstract

An unusual synthesis of functionalized F-alkyl indoles using ethyl perfluoroalkynoates and C,N diphenyl nitrone is described. Two isomers, 2- F-alkyl (90%) and 3- F-alkyl (10%) are obtained with short perfluoro alkyl chains (CF 3, nC 3F 7). Regiospecifity is obtained with longer chains (C 5F 11, C 6F 13, C 7F 15).

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